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Öğe The influence of age on the pharmacokinetics of enrofloxacin and ciprofloxacin in calves - [2](Wiley, 2026) Corum, O.; Yuksel, M.; Corum, D. Durna; Escudero, E.; Marin, P.; Giorgi, M.; Uney, K.[Abstract Not Available]Öğe Changes in cytokine levels at calving in cows with dystocia(Wiley, 2026) Risvanli, A.; Koc, O. Yilmaz[Abstract Not Available]Öğe Fatty acid content and nutritional composition of seeds of certain Triticale varieties - [2](Innovhub Ssi-Area Ssog, 2025) Ozdemir, Selim; Seydosoglu, Seyithan; Kokten, Kagan; Cil, AbdullahTriticale cultivars can be grown for fodder as well as grain. Growing demand for food resources has led to an increased interest in triticale development. This cereal is receiving great attention as an alternative source of nutrients and health-protective components in the human diet. In this study, the lipid content and fatty acid composition of 7 triticale varieties were determined. The lipid content of the examined triticale varieties varied between 0.11 and 1.14%. The major unsaturated fatty acids found in the grain lipids of triticale varieties were oleic (17.16-22.74%), linoleic (53.67-57.84%) and linolenic (4.04-5.01%) acids. Levels of palmitoleic, arachidic, erucic, docosahexaenoic and nervonic acids were found to be lower than 1%. The crude ash (CA) and crude protein (CP) ratios in the grains of triticale varieties varied between 0.75-2.24% and 7.45-9.34%, respectively. The acid detergent fiber (ADF), neutral detergent fibre (NDF) and acid detergent lignin (ADL) ratios of the grains of triticale varieties varied between 7.91-9.04%, 25.34-29.45% and 1.06-2.96%, respectively. The dry matter digestibility (DMD) and dry matter intake (DMI) ratios and relative feed value (RFV) values of triticale grains varied between 81.86-82.74%, 4.08-4.74% and 260.74-302.54, respectively. The Presto, Umranhanim and Alperbey varieties have greater ADL and NDF properties; Aysehanim and Mehmetbey varieties had better ADF and CP ratios; the Tatlicak-97 variety recorded higher total digestible nutrients (TDN), DMD, digestible energy (DE) and metabolic energy (ME) values; the Tacettinbey variety had higher ash content, DMI and relative feed value (RFV).Öğe Regulatory effects of PNX-14 on BPAinduced abnormalities in puberty, steroidogenesis, and reproductive histopathology in male and female rats(Wiley, 2026) Akipek, Mehmet Emre; Ercan, Eda Coban; Akipek, Rumeysa Esra Kom; Atmaca, Ahmet Tuluhan; Ozoner, Merve Pekince; Ozoner, Ozgur; Canpolat, Sinan[Abstract Not Available]Öğe The Effect of Comedy Therapy on Anxiety and Vital Signs in Liver Transplant Recipients during the Preoperative Period: A Randomized Controlled Trial(Wiley, 2026) Saritas, Hasan; Okutan, Serafettin; Bulbuloglu, Semra; Saritas, Serdar; Guven, Durdane YilmazBackground Patients awaiting liver transplantation often experience preoperative anxiety, which may negatively influence vital signs and physiological stability. Brief, low-cost non-pharmacological interventions such as comedy therapy may help reduce anxiety and improve selected physiological parameters. This study aimed to evaluate the effect of comedy therapy on preoperative anxiety and vital signs in liver transplant recipients. Methods This randomized controlled trial was conducted between April 2024 and May 2025 at a liver transplant institute in Turkey. A total of 120 participants were randomly assigned to an intervention group (n = 60) or a control group (n = 60). During the preoperative period, the intervention group watched 10-min clips from classic Turkish comedy films, while the control group received only routine care. State-trait anxiety inventory (STAI) scores and vital signs (systolic/diastolic blood pressure, heart rate, respiratory rate, and oxygen saturation) were measured before and after the intervention. Data were analyzed using SPSS 26 with p < 0.05 considered significant. Results In the intervention group, STAI scores decreased significantly after comedy therapy (p = 0.001), whereas no significant change occurred in the control group (p = 0.974). Mean pulse, systolic and diastolic blood pressure, and respiratory rate decreased, and oxygen saturation increased significantly in the intervention group (p < 0.05). In the control group, only a limited reduction in blood pressure was noted. Between-group comparisons revealed significant differences in respiratory rate and oxygen saturation (p < 0.05). Conclusion Comedy therapy effectively reduces preoperative anxiety and improves selected physiological parameters in liver transplant recipients. Integrating such low-cost, non-pharmacological interventions into surgical preparation may enhance psychological well-being and promote physiological stability.Öğe A novel pruning-enhanced hybrid approach for efficient and accurate brain tumor diagnosis -[2](Elsevier Sci Ltd, 2026) Dogan, YahyaBackground: Accurate and efficient brain tumor diagnosis is a persistent challenge in medical imaging due to the complexity and variability of tumor structures. Deep learning has demonstrated strong potential; however, balancing diagnostic performance with computational efficiency remains a significant barrier to real-world deployment, particularly in resource-limited clinical settings. Proposed Method: This study introduces a novel hybrid framework combining a pruning-enhanced EfficientNetV2B3 model with metaheuristic-based feature selection and traditional machine learning classifiers. Multiple state-of-the-art CNN architectures were initially evaluated, and EfficientNetV2B3 was selected as the most effective model. A sparsity-driven threshold-based pruning strategy was then applied, reducing parameters by approximately 78% (from 12.9M to 2.86M) while retaining competitive classification accuracy. Feature vectors extracted from the pruned model were refined using Genetic Algorithm, Particle Swarm Optimization, and Lion Optimization Algorithm. Results: The pruned EfficientNetV2B3 model maintained high performance, achieving 97.70% +/- 0.11 accuracy. Among all evaluated classifiers, Random Forest combined with genetic Algorithm-selected features yielded the best results: 98.64% +/- 0.25 accuracy, 98.67% +/- 0.24 precision, and 98.66% +/- 0.26 F1-score. Additionally, visualization techniques such as t-SNE and Grad-CAM were used to confirm feature separability and enhance model interpretability. Conclusion/Impact: The proposed hybrid framework demonstrates that significant model compression can be achieved without compromising diagnostic accuracy. It offers a computationally efficient and interpretable solution suitable for deployment in real-time and low-resource clinical environments.Öğe Microbiological changes occurring during storage in kefirs with pomegranate (Punica granatum L.) juicy produced from cow's milk(Hellenic Veterinary Medical Soc, 2026) Hallac, B.; Sancak, H.This research was conducted to determine the microbiological changes that occur during storage (zeroth, 7(th), 14(th), 21(st) and 28(th) days) in kefirs with pomegranate (Punica granatum L.) juicy produced from cow's milk at different concentrations (6.25%, 12.5%, 25%, 50%). Sterile cow's milk, kefir grains, and Zivzik pomegranate juice were used in production. The highest total aerobic mesophilic microorganism (TAMM) count (9.00 +/- 0.35 log(10) CFU/mL) was determined in sample at 50% concentration on the 14(th) day of storage. In the last stages of storage, TAMM counts decreased at all concentrations due to the inhibitory effect of pomegranate juice on microorganisms. The count of coliform group microorganism determined at 3 log(10) CFU/mL levels in all concentrations also partially decreased during storage and Escherichia coli wasn't encountered in samples. However, the count of Lactobacillus spp. increased due to increasing pomegranate juice concentrations and improved fermentation. A statistically significant relationship (p<0.01) was observed between Lactobacillus spp. and coliforms determined in kefir samples. As the storage time was prolonged, fermentation effect was prominently seen in kefirs with pomegranate juicy and a significant relationship (p<0.01) was determined between yeast and mold count and pomegranate juice concentrations. As a result, it was observed that high concentrations of pomegranate juice in kefirs created an inhibitor effect on microorganisms in a generally. The fact that kefirs with pomegranate juicy comply with the criteria indicated in the legislations in terms of E. coli shows that the consumption of these products during storage won't pose any risk to public health. It is thought that individuals who have digestive system problems due to the count of Lactobacillus spp. detected above the level specified in the legislations and increasing during storage can easily use these products containing probiotics. Mold was only prominently reproduced in samples towards the end of the storage, and coliforms, which were thought to have originated from kefir grains used in production, were determined. When quality and hygienic materials are used in production, kefirs with pomegranate juicy that comply with standards and have a shelf life of 21 days' can be produced. Considering the taste and antioxidant activity of pomegranate juice, it is thought that kefirs with pomegranate juicy produced at hygienic conditions can be effective in healthy nutrition and these innovative products can contribute to economic development.Öğe Additive Manufacturing of Cranial Implants: Experimental Evaluation and Machine Learning Prediction of Mechanical and Dimensional Performance(Wiley, 2026) Yildirim, Yagmur Akin; Yildirim, Burak; Ulkir, Osman; Kuncan, MelihThis study investigates the additive manufacturing (AM) of defect-specific cranial implants produced by fused deposition modeling (FDM) using three different polymeric materials, namely polylactic acid (PLA), polyamide (PA), and polyether ether ketone (PEEK). The primary objective is to evaluate the effects of key printing parameters on the dimensional accuracy and mechanical performance of the fabricated implants as well as to develop machine learning (ML) models to predict the main output responses. For this purpose, material type (MT), printing speed (PS), infill density (ID), layer height (LH), and build orientation (BO) were selected as input parameters and organized according to an L27 Taguchi experimental design. The fabricated implants were evaluated in terms of maximum length, thickness, maximum compressive load, and impact resistance. Analysis of variance revealed that MT, ID, LH, and BO affected maximum compressive load, whereas PS was not significant for this response within the investigated range. Gaussian process regression (GPR), support vector regression (SVR), and decision tree regression (DTR) models were used to predict the mechanical responses of the implants. Among them, GPR showed the highest predictive accuracy, achieving for compressive load and for impact resistance.Öğe RuCo@Expanded Perlite Nanocatalyst for Sustainable Hydrogen Generation via Methanolysis of Ammonia Borane(Wiley, 2026) Izgi, Mehmet Sait; Sahin, Omer; Onat, ErhanRuCo nanoclusters supported on expanded perlite (EP) were synthesized and evaluated as efficient catalysts for hydrogen generation via the methanolysis of ammonia borane (AB). EP, an inexpensive and environmentally benign support, was modified to enhance its surface properties and subsequently employed for metal loading. The resulting RuCo@EP catalyst exhibited good activity, achieving a hydrogen generation rate (HGR) of 5487 mL g-1 min-1 and a turnover frequency (TOF) of 94.5 h-1 at 30 degrees C. Comprehensive kinetic studies revealed that the reaction follows first-order kinetics with respect to AB concentration, with an apparent activation energy of 47.07 kJ mol-1. Structural and morphological analyses (XRD, SEM-EDS, TEM, and BET) supported the successful incorporation and relatively uniform distribution of Ru and Co nanoparticles on the perlite surface. These findings demonstrate that RuCo@EP is a cost-effective and highly active catalyst, highlighting the potential of natural mineral supports for sustainable hydrogen generation.Öğe Seed priming and phosphorus fertilization boost nutrient biofortification of lentil plants -[2](Polish Society Magnesium Research, 2025) Ceritoglu, Mustafa; Erman, Murat; Cig, FatihThis experiment investigated effects of seed priming and phosphorus fertilization on the biofortification of lentil plants grown under low-phosphorus field conditions. Four phosphorus doses and six priming treatments were used in the experiment. According to results, 15 and 30 kg P ha-1 significantly increased the nitrogen concentration in plants while all phosphorus doses stimulated greater magnesium accumulation over control. Higher phosphorus addition restricted potassium acquisition by 9.5% under high-potassium soils. Moreover, 15 kg P ha-1 application of salicylic acid, citric acid, inorganic phosphorus or plant growth-promoting bacteria (PGPB) distinctly promoted the uptake of nitrogen, phosphorus, potassium, manganese, iron and zinc. PGPB mostly promoted nitrogen and phosphorus uptake, while citric acid priming highly stimulated the acquisition of Mg, Mn and Fe. All priming treatments were lower than the control for potassium accumulation, in which the lowest value was observed in PGPB-primed plants, because it can solubilize phosphorus compounds in rhizosphere, thereby causing an antagonistic effect on potassium uptake. Seed priming with 4 mM silicon enhanced copper accumulation in tissues up to 9.4%. Priming with 100 mg kg-1 citric acid promoted iron, magnesium and manga- nese accumulation by 13.8%, 3.8% and 4.7% compared with control, respectively. In conclusion, phosphorus addition boosted macro- and micronutrient acquisition, although the 15 kg P ha-1 dose is recommended from an economic perspective. Also, phosphorus application and seed priming treatments exhibited synergistic effects on nutrient acquisition depending on a nutrient element. Finally, seed priming with PGPB, 4 mM salicylic acid and 100 mg kg-1 citric acid exhibited superior performance on nutrient uptake in lentil.Öğe Effect of Ironing Parameters on Surface Quality and Energy Demand ofFDM-Fabricated Proximal Humerus Plates: A Box-Behnken and Machine Learning Study(Wiley, 2026) Altuncu, Mehmet Ali; Ulkir, Osman; Kuncan, MelihThis study investigates the effects of ironing parameters on surface quality and energy demand in FDM fabrication of proximal-humerus-inspired PLA plate-like demonstrator, aiming to quantify how ironing settings influence surface roughness (Ra) and electrical energy consumption (EC), thereby revealing the quality-efficiency trade-off in the finishing stage. Four ironing related process variables including ironing flow (IF), ironing line spacing (ILS), ironing speed (IS), and ironing inset (II) were investigated at three levels using a BBD. Experimental results showed that Ra varied between 4.52 and 8.52 mu m, whereas EC ranged from 261.15 to 545.39 Wh, indicating that improved surface finish generally requires higher energy input. Analysis of variance confirmed that IF, ILS, and IS significantly affect Ra (p < 0.001), while EC is predominantly governed by IS and IF (p < 0.001). To model and predict Ra and EC from ironing parameters, LR, ANN, and GPR-Bayes models were developed and evaluated using a repeated group-based fivefold cross-validation strategy. For Ra prediction, LR and GPR-Bayes showed similar performance, while ANN showed lower performance. For EC prediction, GPR-Bayes achieved the best overall performance, with R-2 = 0.8624 +/- 0.1741.Öğe Nitrogen-Doped Graphitic Carbon Nitride With Defect-Rich Structure for Efficient Pb (II) and Cd (II) Removal From Aqueous Solutions(Wiley, 2026) Saka, Cafer; Tegin, Ibrahim; Baykara, RabiaThe presence of toxic heavy metals such as Pb (II) and Cd (II) in water poses severe risks to ecosystems and human health. In this study, nitrogen-doped graphitic carbon nitride (N@g-C3N4) was synthesized via an ammonia-assisted hydrothermal route to enhance its adsorption performance toward Pb (II) and Cd (II) ions. Structural and surface analyses confirmed that nitrogen heteroatom doping generated abundant defect sites and nitrogen-containing functional groups, significantly improving surface reactivity compared to pristine g-C3N4. Batch adsorption experiments revealed that N@g-C3N4 exhibits markedly enhanced adsorption capacity, strongly dependent on solution pH, contact time, and temperature. The adsorption isotherms were well described by the Langmuir model, indicating monolayer adsorption on homogeneous active sites. Kinetic data followed the pseudo-first-order model, suggesting a surface-controlled adsorption process. Thermodynamic analysis demonstrated that the adsorption of both Pb (II) and Cd (II) is spontaneous and endothermic. The enhanced performance is attributed to synergistic electrostatic attraction, surface complexation, and coordination interactions between metal ions and nitrogen-rich functional groups. This work highlights nitrogen heteroatom engineering as an effective strategy to develop high-performance g-C3N4-based adsorbents for wastewater treatment.Öğe Experimental and Theoretical Investigation of Ammonia Borane Dehydrogenation Using an Aniline-Enhanced Ru Nanocatalyst(Wiley-V C H Verlag Gmbh, 2026) Izgi, Mehmet Sait; Sahin, Omer; Onat, Erhan; Enisoglu, Muhammed; Celik, Fatih Ahmet; Karabulut, EzmanThis study aimed to synthesize carbon quantum dots (CQDs) through the interaction of carboxyl (-COOH) and amino (-NH2) groups and to investigate experimentally and theoretically hydrogen (H2) production efficiency from ammonia borane (AB) hydrogen source using this CQDs structure with ruthenium (Ru) catalyst support material. CQDs were obtained by the hydrothermal method from aniline (A) and trichloroacetic acid (TCA) under weak base-acid coupling. A heterogeneous Ru@ATCA catalyst is developed using Ru metal nanoclusters decorated on CQDs. The development process is characterized by advanced analytical methods (UV, PL, BET, ICP-OES, TEM, XPS, XRD). As a result of the AB catalytic reaction at 298 K, a very high Hydrogen Production Rate (HGR) of 102.1 L/g.min and a catalyst cycle frequency (TOF) of 356 min-1 are obtained. The reaction proceeds in a first-order manner, with activation energy (Ea) of 22.3 kJ/mol, activation enthalpy and entropy of 19.65 and -29.95 J/mol, respectively. The mesoporous structures under this interaction, the increase in active surface area increases H2 production efficiency by providing lower viscosity for both AB hydrolysis and the surrounding molecular groups. The H2 production efficiency is compared with GFN1xTB modeling. According to modeling, the Ru activity of the weak acid TCA alone has a weaker catalytic effect than the Ru activity resulting from its interaction with the weak base aniline molecule, demonstrating the importance of the weak acid and weak base interactions.Öğe Kinetic Evaluation and Fabrication of Co-Fe-B Catalyst in Ethanol for Rapid Hydrogen Production From Sodium Borohydride(Wiley-V C H Verlag Gmbh, 2026) Keskin, Mehmet Salih; Agirtas, Mehmet SalihIn this study, Co-Fe-B catalysts were synthesized separately in ethanol and aqueous media under ambient conditions using a chemical reduction-precipitation method for rapid and efficient hydrogen generation from sodium borohydride (NaBH4) hydrolysis. The structural and morphological properties of the synthesized catalysts were characterized by SEM-EDX and XRD analyses. The results demonstrated that the synthesis medium had a significant influence on the catalytic performance. At 30 degrees C, the hydrogen generation rate of the Co-Fe-B catalyst synthesized in ethanol reached 13,021.6 mL gcat-1 min-1, whereas the catalyst synthesized in water exhibited a hydrogen generation rate of 4005 mL gcat-1 min-1 under the same conditions. The hydrogen generation rate increased with increasing temperature, catalyst amount, and NaBH4 concentration. The reaction order was determined to be approximately 0.9, and the activation energy of the highly active catalyst was calculated as 37.72 kJ mol-1 using the Arrhenius equation. The enhanced catalytic activity of the catalyst synthesized in ethanol was attributed to the formation of a larger active surface area and electron transfer from boron to the active Co and Fe sites. These findings reveal that the synthesis medium plays a critical role in determining the structural properties and hydrogen generation performance of Co-Fe-B catalysts.Öğe MusicoCrypt: A Music-Modulated Stream Cipher Using Deep Pitch Estimation and Number-Theoretic Dynamics(Wiley, 2026) Turan, Cilen Gulsum; Keskin, Fesih; Isik, GultekinThis paper presents MusicoCrypt, a context-bound music-modulated stream-encryption framework that incorporates audio-derived public side information into a pseudorandom-function-centered encryption workflow. A shared reference recording is processed using a pitch-tracking pipeline, and ordered note pairs are encoded as residues in to form a contextual carrier. We first analyze MusicoCrypt-Core, a raw affine construction in which HMAC-SHA256-derived table indices select Happy-number and Collatz-based coefficients for carrier modulation. Motivated by the observed statistical bias of this raw affine stream, we introduce MusicoCrypt-W, a bias-resistant variant in which the audio-derived carrier and affine residue are used as domain-separated inputs to a final HMAC-SHA256 extraction layer with unbiased rejection sampling over . A byte-oriented MusicoCrypt-WB interface is also defined for binary protocols and standardized bit-level testing. The evaluation includes long-sequence stream statistics, HMAC-only/audio-hash/carrier ablations, NIST SP 800-22 bit-level tests, fixed-budget extraction analysis, known-plaintext analysis, frame-resynchronization simulation, acoustic synchronization experiments under additive white Gaussian noise, and computational-cost measurements that separate offline carrier extraction from online keystream generation. Results on symbols show that the raw Core keystream remains detectably non-uniform, whereas MusicoCrypt-W is consistent with the expected uniform distribution in the reported symbol-domain chi-square test. The ablation study shows that HMAC-based extraction provides the final statistical behavior, while the audio context provides context binding and cross-context separation. Accordingly, MusicoCrypt is positioned for context-bound multimedia workflows where offline carrier extraction is acceptable, rather than as a replacement for lightweight real-time binary stream ciphers.Öğe Optimization of Ultrasound-Assisted Extraction of Thymbra Spicata L. Using Response Surface Methodology: Polyphenol Profile and Antibacterial Activity(Wiley-V C H Verlag Gmbh, 2026) Sirin, Muhammed Hasan; Kaya, Muhammet Mukerrem; Demirag, Melike Sultan; Keyvan, Erhan; Bayezit, Murat; Tutun, HidayetThymbra spicata L. (Zahter) is a medicinal aromatic plant naturally growing in T & uuml;rkiye. This study aimed to optimize ultrasound-assisted extraction (UAE) conditions using response surface methodology (RSM) to maximize its total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (DPPH). The optimal conditions were established as 31.071% methanol, 63.467 degrees C, 48.423 min, and a 36.14 mL/g solvent-to-solid ratio. The optimized extract yielded TPC, TFC, and DPPH values of 145.77 +/- 2.26 mg GAE/g, 16.19 +/- 0.20 mg QE/g, and 97.794 +/- 1.78 mg AAE/g dry plant material, respectively, demonstrating positive correlations among them. Orbitrap-MS profiling identified rosmarinic acid, quinic acid, luteolin-7-O-glucuronide, and naringenin as the predominant polyphenols. Furthermore, antibacterial assays revealed minimum inhibitory (MIC) and bactericidal (MBC) concentrations of 5 and 10 mg/mL, respectively, against Salmonella Typhimurium and Listeria monocytogenes, whereas values for Escherichia coli O157:H7 were >10 mg/mL. Conclusively, RSM optimization successfully yielded a polyphenolic-rich T. spicata extract with high antioxidant capacity and measurable antibacterial activity at higher concentrations.Öğe Optimization and Molecular Simulation of Gelatin-Free Marshmallow Formulation Using Gellan Gum and Aquafaba(Wiley, 2026) Telli, Elif Ersahin; Goztok, Serpil Pekdogan; Palabiyik, Ibrahim; Kamer, Deniz D. A.; Konar, NevzatThis study aimed to optimize the formulation of marshmallow-type products by replacing animal-derived gelatin with plant-based aquafaba and gellan gum. The formulation optimization was conducted using response surface methodology, with the optimal formulation determined based on the density and overall preference. In the optimized formulation, the inclusion rates of aquafaba and gellan gum as gelatin substitutes were determined to be 0.71% and 0.50%, respectively. The marshmallow samples were compared to control marshmallow samples containing gelatin (CM). The interaction between aquafaba and gellan gum was further investigated using molecular docking. The most stable predicted molecular configuration yielded a binding energy score of -9.8 kcal/mol, suggesting a favorable interaction. The water activity, density, and T-end values of the optimized formulation (OFM) samples were 0.56, 0.84 g/cm(3), and 81.65 degrees C, respectively, all of which were higher than those of the CM samples. A significant difference was observed in the color values between the OFM and CM samples, despite no colorants being used in either formulation (p < 0.05). The PLM images revealed that the granule dimensions in the CM samples were larger and more prominent compared to the OFM samples. The OFM samples also exhibited higher viscosity and superior viscous rheological properties compared to the CM samples.Öğe Macroscopic, Histological and Ultrastructural Features of the Tongue of the Anatolian Wild Boar (Sus scrofa libycus)(Wiley, 2026) Isbilir, Fatma; Kandil, Banu; Atli, Muhammed Zahid; Isbilir, Ihsan; Guzel, Baris CanThis study provides a detailed characterization of the macroscopic anatomy and microscopic features (light and scanning electron microscopy) of the lingual papillae in the adult Anatolian wild boar (Sus scrofa libycus). Tissue samples were taken from two adult wild boars found dead in their natural habitat within an average of 1.5 h. Following macroscopic observation, samples underwent routine histological processing, histochemical staining, and high-resolution surface morphology analysis via scanning electron microscopy (SEM). Morphological analysis revealed five distinct types of papillae: filiform, fungiform, conical, foliate, and vallate. Filiform papillae, exhibiting either sharp or blunt apices, showed structural adaptations specialized for mechanical function. Fungiform papillae were identified in circular and oval forms; notably, taste buds were restricted to the circular type. Foliate papillae, comprising 3-5 distinct folds, lacked taste buds. A pair of vallate papillae, each demarcated by a prominent trench and housing lateral taste buds, was observed on the caudal tongue. Histochemical evaluation using Periodic Acid-Schiff (PAS) and Alcian Blue (AB) confirmed the presence of both neutral and acidic mucins within the lingual glands. These findings suggest that the lingual morphology of the Anatolian wild boar is closely adapted to its specific dietary habits and ecological niche. This data serves as a critical baseline for comparative anatomy, forensic veterinary medicine, and future morphological research.Öğe Examining the Psychometric Properties of Four Mattering Constructs Through Rasch Modeling: Evidence From Turkish Adolescents and College Students(Wiley, 2026) Kaya, Alican; Green, Zane Asher; Sata, Mehmet; Yildirim, Murat; Sarigul, Abdulselami; Turk, Nuri; Duradoni, MirkoBackground Mattering and anti-mattering are central constructs in understanding individual well-being. Traditionally, these concepts have been studied in offline social contexts. The rise of information and communication technologies has expanded the social environments in which individuals may feel valued or, conversely, insignificant. However, evidence on measurement invariance of these combined offline and online mattering scales for gender and different developmental stages remains limited in culturally diverse countries, including Turkey.Objectives This study aimed to validate four scales assessing both offline and online dimensions of mattering and anti-mattering-the General Mattering Scale, the Anti-Mattering Scale, the Online Mattering Scale, and the Online Anti-Mattering Scale-within a Turkish sample of adolescents and college students.Methods: Data were collected from 888 participants (high school students: n = 434, mean age = 15.51 +/- 1.02, 63.1% female; college students: n = 454, mean age = 21.10 +/- 1.67, 84.1% female). Confirmatory factor analyses (CFA) were conducted to examine the dimensional structure and reliability of the scales. Additionally, the Many-Facet Rasch Model (MFRM) was applied to test measurement invariance across educational levels and gender.Results CFA results indicated acceptable fit indices for all four scales across both groups, with reliability coefficients exceeding recommended thresholds. MFRM analyses further supported measurement invariance across high school and college students, as well as across male and female participants.Conclusion The four-scale set appears psychometrically sound for use with Turkish adolescents and emerging adults and is well-suited to capturing the complexity of contemporary hybrid social environments, where experiences of significance and neglect can occur both offline and online.Öğe Insecticidal Potential of Essential Oils from Origanum onites, Lavandula angustifolia, and Foeniculum vulgare Against Agonoscena pistaciae: Integrated In Vitro and In Silico Approaches(Wiley-V C H Verlag Gmbh, 2026) Yas, Cemile; Dilmen, Halil; Gok, Mesut; Basar, YunusThis study evaluated the insecticidal potential of essential oils (EOs) obtained from Origanum onites, Lavandula angustifolia, and Foeniculum vulgare against Agonoscena pistaciae. The phytochemical content of the essential oils was determined by GC-MS. Furthermore, molecular docking analyses were performed to theoretically investigate the inhibitory properties of the dominant compounds against the detoxification enzymes glutathione S-transferase (GST) and cytochrome P450. In the GC-MS analysis, the dominant components were identified as follows: O. onites (60.51% carvacrol, 9.73% linalool, and 7.53% cis-cymene); L. angustifolia (25.44% linalyl acetate, 23.47% linalool, and 7.37% cis-cymene); and F. vulgare (49.41% anethol, 14.62% p-anisaldehyde, and 9.35% estragol). As a result of molecular docking, carvacrol showed the strongest binding affinity to both enzymes, surpassing the reference inhibitors metronidazole and coniferil ferulate, achieving docking scores of -5.40 kcal/mol and -5.70 kcal/mol, respectively. Visualization of molecular interactions revealed strong hydrogen bonds and hydrophobic contacts between carvacrol and the enzyme active sites. Biological analyses confirmed that carvacrol-rich O. onites EOs caused significantly higher mortality rates in A. pistaciae larvae compared to other applications and controls. These results demonstrate that carvacrol derived from O. onites is a promising natural insecticide targeting detoxification enzymes in pests and offering a sustainable alternative to synthetic pesticides.
