STABILITY ANALYSIS OF DELAYED CO-INFECTION MODEL OF PNEUMONIA AND MENINGITIS

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Tarih

2026

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Science & Knowledge Publ Corp Ltd

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

This study develops and analyzes a delay differential model to investigate the co-infection dynamics of pneumonia and meningitis in a human population. The model incorporates biologically motivated delay factors-such as isolation, social distancing, and public awareness represented through an exponential survival term. These delays capture the influence of behavioral and treatment-related interventions on disease transmission. The model's dynamical behavior is examined through the analysis of positivity, boundedness, and equilibrium states. Both the disease-free equilibrium (DFE) and disease-existing equilibrium (DEE) are shown to be locally and globally asymptotically stable under appropriate threshold conditions. Sensitivity analysis highlights the influence of key parameters, including delay-related terms, on the basic reproduction numbers of pneumonia, meningitis, and their co-infection subsystem. Numerical simulations support the analytical results and illustrate how increasing delay-based interventions can effectively suppress disease spread. The findings provide valuable insights for public health strategies, suggesting that isolation, social distancing, and awareness campaigns can substantially mitigate co-infection risks in affected communities.

Açıklama

Anahtar Kelimeler

Co-Infection, Delay, Equilibrium, Reproduction Number, Stability

Kaynak

Communications in Mathematical Biology and Neuroscience

WoS Q Değeri

Q4

Scopus Q Değeri

Cilt

2026

Sayı

Künye