Evaluation of Infection Factor and Antibiotic Resistance Distributions in Palliative Care Patients Developed Urinary Tract Infection

Abstract

Objectives: In this study, it was aimed to identify the causative bacteria of urinary tract infections, to determine antibiotic susceptibility, and to examine acute phase markers in patients hospitalized in the palliative care service of Ankara Polatli Duatepe State Hospital between January 2019 and December 2020. Materials and Methods: These sex, age and, detected diseases of a total of 72 palliative care patients included in our study were analyzed retrospectively. To determine the causative agents of urinary tract infections in these patients, Gram staining was performed on the bacterial cultures that developed in the urine samples, and the Vitek-2 (bioMerieux, France) automatic test device was used to identify these cultures and determine their antibiotic susceptibility. In the blood sample staken from these patients, leukocyte (WBC), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) measurements were also made. Results: The causative agents of urinary tract infections of these patients are Gram-negative bacteria Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Acinetobacter baumannii, Citrobacter koseri, Morganella morganii ssp. morganii, Enterobacter cloacae complex, and Gram-positive bacteria Enterococcus faecium, Enterococcus spp., and Staphylococcus epidermidis were found. Various antibiotics were determined to have different levels of sensitivity. Conclusions: It is important to determine the causative agents of urinary tract infections, which are among the most frequently detected infections in palliative care patients, and to determine antibiotic susceptibility and acute phase response markers fo these agents. Mortality and morbidity will be reduced by determining the causative agents of these infections and applying appropriate antibiotic treatments.