Change of Vitamin D Levels According to Age, Gender and Seasons in ??rnak Province

Abstract

Objective: This study determines the 25-hydroxy vitamin D [25(OH)D] profile according to season, age, and gender by examining the vitamin D levels of the patients who applied to Cizre State Hospital, which is the warmest district of Turkey, in 2021.Materials and Methods: 13,387 patients admitted to Cizre State Hospital were included in the study, and their [25(OH)D] levels were analyzed retrospectively. In the study, [25(OH)D] levels were evaluated according to the age, gender and seasonal differences of the patients. [25(OH)D] levels in serum are <12 ng/mL, severe deficiency, 12-20 ng/mL mild-moderate deficiency, 21-30 ng/mL insufficient, >30 ng/mL conditions were accepted as qualifications. Results: The findings of 9,800 women and 3,587 men were evaluated in the study. The mean serum level of [25 (OH)D] was 12.31 +/- 0.08 ng/ mL in women and 17.58 +/- 0.15 ng/mL in men. Amongst the age groups, vitamin D levels in both male and female patients were statistically significant (p<0.01). Statistically significant changes were identified across seasons, with [25(OH)D] levels in both women and men being lowest in winter and greatest in summer (p<0.01).The mean [25(OH)D] level was 18.51 +/- 0.17 ng/mL in patients aged 0-15 years (n=3,219), 11.86 +/- 0.12 ng/mL in patients aged 16-30 years (n=4,093), between 31-45 years old 12.12 +/- 0.14 ng/mL in patients (n=3,008), 12.39 +/- 0.18 ng/mL in patients aged 46-60 years (n=1,817), and 13.40 +/- 0.28ng/mL in patients aged 61-75 years (n=962).Conclusion: In this study, very serious vitamin D deficiency was detected in patients admitted to Cizre State Hospital. It is thought that low vitamin D levels may be related to the absence of vitamin D synthesis because of insufficient sunlight in winter, the closed dressing habits of the region, or foods deficient in vitamin D. Because of this study, the need for supportive treatment gained more importance.