The Importance of Blood Parameters for Prognosis Prediction in Status

Aim: To compare blood parameters between patients with status epilepticus (SE) and those with non-SE epileptic seizures at presentation to the emergency department, and to evaluate the prognostic value of immature granulocytes (IG). Materials and Methods: This retrospective study included adult patients presenting with seizures. Hematological and biochemical parameters, including C-reactive protein (CRP), white blood cell count (WBC), blood gas parameters, IG, and IG%were analyzed. Results: A total of 634 patients were screened; 68 hospitalized patients who met the inclusion criteria were analyzed (SE: n=37; non-SE: n=31). Significant differences between groups were observed for WBC, lactate, pH, bicarbonate (HCO3-), base deficit, CRP, IG, and IG%(p<0.05 for all). An IG cut-off value of 0.045 predicted clinical outcomes with 95.8% sensitivity and 97.7% specificity. Conclusion: IG and IG%are promising, rapid, and cost-effective inflammatory biomarkers with high diagnostic accuracy in SE. Their use may support early risk stratification, guide clinical decision-making, and improve timely intervention in emergency settings.