Reference Intervals for Schirmer Tear Test and Intraocular Pressure in Healthy Hamdani Crossbred Sheep

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dc.contributor.authorSulu, Kadir
dc.contributor.authorAkgul, Mustafa Baris
dc.contributor.authorGulaydin, Ali
dc.contributor.authorYilmaz, Maruf
dc.contributor.authorErden, Bahar
dc.contributor.authorTurgut, Ali Osman
dc.date.accessioned2026-10-23T18:14:13Z
dc.date.available2026-10-23T18:14:13Z
dc.date.issued2026
dc.departmentSiirt Üniversitesi
dc.description.abstractBackground Breed-specific reference intervals for the Schirmer tear test (STT) and intraocular pressure (IOP) in Hamdani crossbred sheep have not been established. Objectives To determine reference intervals for STT and IOP in healthy Hamdani crossbred sheep. Methods A total of 200 clinically healthy animals were stratified into four age groups: < 6 months, 6 months to 1 year, 1-2 years, and > 2 years. Each group comprised equal numbers of males (n = 25) and females (n = 25). Tear production was evaluated using STT-1, and IOP was measured with a rebound tonometer. Group-based mean values were calculated using representative values obtained by averaging measurements from both eyes. Results Mean values and reference intervals for STT and IOP were established for each age group. No sex-related differences were observed in STT values. However, age-related differences were observed only in females, with higher STT values in hoggets than lambs (p < 0.01). For IOP, ewes had higher values than rams (p < 0.01). Age-related differences in IOP were observed only in males, with rams showing lower IOP values than suckling lambs and hoggets (p < 0.01). Conclusions This study establishes reference intervals for STT and IOP in healthy Hamdani crossbred sheep and provides clinically relevant baseline data for ophthalmic assessment.
dc.description.sponsorshipSiirt University Scientific Research Projects Coordinatorship [2025-SIdot;VET-012] -- This study was supported by the Siirt University Scientific Research Projects Coordinatorship (Project No. 2025-S & Idot;UVET-012). Artificial intelligence-assisted tools were used solely for language editing and proofreading and had no influence on the scientific content, data interpretation, or conclusions. All authors reviewed and approved the final version of the manuscript and take full responsibility for its content.
dc.identifier.doi10.1002/vms3.71018
dc.identifier.issn2053-1095
dc.identifier.issue4
dc.identifier.orcid0000-0002-7200-1040
dc.identifier.orcid0000-0002-9365-9925
dc.identifier.pmid42237884
dc.identifier.scopus2-s2.0-105040988615
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1002/vms3.71018
dc.identifier.urihttps://hdl.handle.net/20.500.12604/12334
dc.identifier.volume12
dc.identifier.wosWOS:001784449800001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofVeterinary Medicine and Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20261017
dc.subjectHamdani Crossbred Sheep
dc.subjectIntraocular Pressure
dc.subjectReference Intervals
dc.subjectSchirmer Tear Test
dc.titleReference Intervals for Schirmer Tear Test and Intraocular Pressure in Healthy Hamdani Crossbred Sheep
dc.typeArticle

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